null

SMILES ONS(=O)(=O)c1ccccc1

InChI Key InChIKey=BRMDATNYMUMZLN-UHFFFAOYSA-N

PDB links: 2 PDB IDs match this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 11372   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Universita degli Studi

LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataKi:  26nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
TargetCarbonic anhydrase 4(Bos taurus (bovine))
Universita degli Studi

LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataKi:  74nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736P45PubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
Universita degli Studi

LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataKi:  1.80E+4nMAssay Description:Initial rates of 4-nitrophenyl acetate hydrolysis catalyzed by different CA isozymes were monitored spectrophotometrically at 400 nm. A molar absorpt...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736P45PubMed
Target72 kDa type IV collagenase(Homo sapiens (Human))
Universita degli Studi

LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataKi:  7.00E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736P45PubMed
TargetNeutrophil collagenase(Homo sapiens (Human))
Universita degli Studi

LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataKi:  7.40E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736P45PubMed
TargetMatrix metalloproteinase-9(Homo sapiens (Human))
Universita degli Studi

LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataKi:  7.80E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736P45PubMed
TargetInterstitial collagenase(Homo sapiens (Human))
Universita degli Studi

LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataKi:  7.90E+4nMAssay Description:Initial rates for the hydrolysis of the thioester substrate AcProLeuGly-S-LeuLeuGlyOEt, coupled to the reaction with 5,5-dithiobis(2-nitrobenzoic aci...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736P45PubMed
TargetCollagenase ColG(Clostridium histolyticum)
Universita degli Studi

LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataKi:  8.30E+4nMAssay Description:The rate of hydrolysis was determined from the change in absorbance at 324 nm using an extinction coefficient, 24700 M-1 cm-1 for FALGPA. Initial vel...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2736P45PubMed
TargetAldehyde dehydrogenase 1A1(Rattus norvegicus)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM11372(CHEMBL55310 | Hydroxysulfonamide 53 | N-hydroxyben...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:In vitro inhibition against yeast Alcohol dehydrogenaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q25T3JHXPubMed