null

SMILES CC(=O)N1CCN(CCN2C=Cc3cc(sc3S2(=O)=O)S(N)(=O)=O)CC1

InChI Key InChIKey=DUEFHDPFDCMJLM-UHFFFAOYSA-N

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 11395   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11395(2-[2-(4-acetylpiperazin-1-yl)ethyl]-1,1-dioxo-2H-1...)copy SMILEScopy InChI
Affinity DataKi:  0.25nM ΔG°:  -13.6kcal/molepH: 7.4 T: 2°CAssay Description:Inhibitor binding to CA II was determined using a fluorescence competition assay. Displacement of dansylamide and binding of the inhibitor was determ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed
TargetCarbonic anhydrase 2(Homo sapiens (Human))
Alcon Research, Ltd.

LigandPNGBDBM11395(2-[2-(4-acetylpiperazin-1-yl)ethyl]-1,1-dioxo-2H-1...)copy SMILEScopy InChI
Affinity DataIC50: 0.960nMpH: 7.2 T: 2°CAssay Description:The assay measured the rate of CO2 hydration by determining the addition rate of a NaOH solution using a Radiometer VIT 90 titration system. The enzy...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q23B5XC0PubMed