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SMILES Nc1c(F)cc(cc1Br)S(N)(=O)=O

InChI Key InChIKey=GKYQTYGVQVABPW-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 11606   

TargetCarbonic anhydrase 2(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11606(β-CA inhibitor, 5 | 4-Amino-5-bromo-3-fluorob...)copy SMILEScopy InChI
Affinity DataKi:  33nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CR9PubMed
TargetCarbonic anhydrase 9(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11606(β-CA inhibitor, 5 | 4-Amino-5-bromo-3-fluorob...)copy SMILEScopy InChI
Affinity DataKi:  69nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CR9PubMed
TargetCarbonic anhydrase 4(Bos taurus (bovine))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11606(β-CA inhibitor, 5 | 4-Amino-5-bromo-3-fluorob...)copy SMILEScopy InChI
Affinity DataKi:  113nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CR9PubMed
TargetBeta-carbonic anhydrase 1(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11606(β-CA inhibitor, 5 | 4-Amino-5-bromo-3-fluorob...)copy SMILEScopy InChI
Affinity DataKi:  940nM ΔG°:  -8.22kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed
TargetSiderophore-binding protein(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11606(β-CA inhibitor, 5 | 4-Amino-5-bromo-3-fluorob...)copy SMILEScopy InChI
Affinity DataKi:  3.19E+3nM ΔG°:  -7.49kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed
TargetCarbonic anhydrase 1(Homo sapiens (Human))
University of Agricultural Sciences and Veterinary Medicine

LigandPNGBDBM11606(β-CA inhibitor, 5 | 4-Amino-5-bromo-3-fluorob...)copy SMILEScopy InChI
Affinity DataKi:  3.90E+3nMAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA-catalyzed CO2 hydration activity. Phenol red has been used as indic...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2XK8CR9PubMed
TargetCarbonic anhydrase 2(Mycobacterium tuberculosis)
Università degli Studi di Firenze

LigandPNGBDBM11606(β-CA inhibitor, 5 | 4-Amino-5-bromo-3-fluorob...)copy SMILEScopy InChI
Affinity DataKi:  4.31E+3nM ΔG°:  -7.31kcal/molepH: 8.3 T: 2°CAssay Description:An Applied Photophysics stopped-flow instrument has been used for assaying the CA catalysed CO2 hydration activity [Khalifah et al., J. Biol. Chem., ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28C9V4FPubMed