null

SMILES CC1(C)CCC(=CC1)c1cc(CC(=O)NCCCO)ccc1NC(=O)c1ncc([nH]1)C#N

InChI Key InChIKey=YXGAVVOMJBANIK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 119041   

TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica, N.V.

US Patent
LigandPNGBDBM119041(CHEMBL3086172 | US8674100, 54 | US9221797, 54)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CSF-...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23777CFUS Patent
TargetMacrophage colony-stimulating factor 1 receptor(Homo sapiens (Human))
Janssen Pharmaceutical Research& Development LLC

Curated by ChEMBL
LigandPNGBDBM119041(CHEMBL3086172 | US8674100, 54 | US9221797, 54)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMAssay Description:Inhibition of FMS (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54RHPubMed
TargetMacrophage colony-stimulating factor 1 receptor(Mus musculus (Mouse))
Janssen Pharmaceutica, N.V.

US Patent
LigandPNGBDBM119041(CHEMBL3086172 | US8674100, 54 | US9221797, 54)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:Inhibition of FMS in mouse BMDM cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2MP54RHPubMed
TargetMacrophage colony-stimulating factor 1 receptor [555-568](Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM119041(CHEMBL3086172 | US8674100, 54 | US9221797, 54)copy SMILEScopy InChI
Affinity DataIC50: 2.40nMpH: 7.5Assay Description:A fluorescence polarization competition immunoassay was used to measure compound inhibition of CSF-1R phosphorylation of tyrosine on a synthetic CS...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2W37V4HUS Patent