null

SMILES OP(O)(=O)C(F)(F)c1ccc(CC(Cc2ccc(cc2)-c2ccccc2)(c2ccccc2)n2nnc3ccccc23)cc1

InChI Key InChIKey=UTZGYWMRZLQRNA-UHFFFAOYSA-N

PDB links: 3 PDB IDs contain this monomer as substructures. 3 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 13598   

TargetTyrosine-protein phosphatase non-receptor type 1 [1-298](Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 38nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMpH: 6.3 T: 2°CAssay Description:Hydrolysis of substrate FDP was monitored continuously on a Cytofluor microplate reader with excitation and emission wavelengths set at 440 and 515 ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HX19XSPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 6.90E+4nMAssay Description:Inhibitory activity against CD45 protein-tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
TargetTyrosine-protein phosphatase non-receptor type 2(Homo sapiens (Human))
Merck Research Laboratories

LigandPNGBDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 24nMAssay Description:Inhibitory activity against T cell protein tyrosine phosphataseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 38nMAssay Description:Inhibitory activity against protein tyrosine phosphatase 1B (PTP1B) was determined in fluorescein diphosphate (FDP) assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
Merck Frosst Centre for Therapeutic Research

Curated by ChEMBL
LigandPNGBDBM13598(({4-[2-(1H-1,2,3-benzotriazol-1-yl)-2-phenyl-3-(4-...)copy SMILEScopy InChI
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory activity against Protein tyrosine phosphatase 1B (PTP1B) overexpressed in intact Sf9 cell assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q24M9404PubMed