null

SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@@H]4C(O)=O)n(Cc4c(F)cc(Br)cc4F)c3c2)c(F)c1

InChI Key InChIKey=DFFLXQIRNUPBJI-OALUTQOASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 145770   

TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Janssen Pharmaceutica NV

US Patent
LigandPNGBDBM145770(US8952177, 124 | US9089569, 124 | US9695149, 124)copy SMILEScopy InChI
Affinity DataKi:  0.520nMAssay Description:FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73CFWUS Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
JANSSEN PHARMACEUTICA NV

US Patent
LigandPNGBDBM145770(US8952177, 124 | US9089569, 124 | US9695149, 124)copy SMILEScopy InChI
Affinity DataKi:  0.520nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Q52MSCUS Patent
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
JANSSEN PHARMACEUTICA NV

US Patent
LigandPNGBDBM145770(US8952177, 124 | US9089569, 124 | US9695149, 124)copy SMILEScopy InChI
Affinity DataKi:  0.520nMAssay Description:The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23X85DBUS Patent