null

SMILES CCCNNC(=O)c1ccc(Br)cc1

InChI Key InChIKey=OTHBGAGRQLSYFV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 163628   

TargetHistone deacetylase 1/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 2/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 3.88E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 3/Nuclear receptor corepressor 2 [395-498](Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 6(Homo sapiens (Human))
University of Florida College of Medicine; Northwest Agriculture and Forestry University

LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 4.63E+3nMAssay Description:Purified HDAC1, HDAC2, and HDAC3 (in complex with the deacetylase activation domain of the human NCOR2 (amino acids 395¿498)) were obtained from BPS ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3D48PubMed
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M048J6US Patent
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 3.88E+3nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M048J6US Patent
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 220nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445RM9
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 3.88E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 220nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone deacetylase 1(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 1.70E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445RM9
TargetHistone deacetylase 2(Homo sapiens (Human))
University of Florida Research Foundation, Inc.; The Scripps Research Institute

US Patent
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 3.88E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2445RM9
TargetHistone deacetylase 3(Homo sapiens (Human))TBA
LigandPNGBDBM163628(SR-3212 | US10807944, Compound RLS2-137 | US117319...)copy SMILEScopy InChI
Affinity DataIC50: 220nMAssay Description:These SAR data indicate that a tripartite structure of this scaffold with a central —C(O)—NH—NH— unit flanked by a phenyl group and a short aliphatic...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M048J6US Patent