null

SMILES [H][C@@]12CCC(=O)[C@@]1(C)CC[C@@]1([H])[C@@]2([H])CC[C@@]2([H])C[C@H](O)CC[C@]12C

InChI Key InChIKey=QGXBDMJGAMFCBF-HLUDHZFRSA-N

PDB links: 3 PDB IDs match this monomer.

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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 17639   

TargetCorticosteroid-binding globulin(Homo sapiens)
Nippon Zoki Pharmaceutical Company Ltd.

Curated by ChEMBL
LigandPNGBDBM17639((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...)copy SMILEScopy InChI
Affinity DataKi:  2.46E+3nMAssay Description:Binding affinity to human CBG receptor (corticosteroid-binding globulins)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WM1H5QPubMed
TargetSolute carrier organic anion transporter family member 1A1(Rattus norvegicus)
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM17639((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...)copy SMILEScopy InChI
Affinity DataKi:  1.06E+4nMAssay Description:TP_TRANSPORTER: inhibition of E217betaG uptake in Oatp1-expressing HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20K29V5PubMed
TargetAndrogen receptor(Rattus norvegicus (Rat))
University of Basel

Curated by ChEMBL
LigandPNGBDBM17639((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...)copy SMILEScopy InChI
Affinity DataIC50: 4.07E+4nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TM7CBZPubMed
TargetGlucose-6-phosphate 1-dehydrogenase(Homo sapiens (Human))
University of Manchester

Curated by ChEMBL
LigandPNGBDBM17639((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Inhibition of human recombinant N-terminal His tagged G6PD expressed in Escherichia coli JM109 (DE3) cells assessed as production of NADPH after 30 m...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q298883VPubMed
TargetSex hormone-binding globulin(Homo sapiens (Human))
University of British Columbia

Curated by ChEMBL
LigandPNGBDBM17639((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...)copy SMILEScopy InChI
Affinity DataKd:  71nMAssay Description:Displacement of [3H]5alpha dihydrotestosterone from human sex hormone binding globulinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2RX9DC2PubMed
Target17-beta-hydroxysteroid dehydrogenase type 3(Rattus norvegicus)
CHU de Qu£bec-Research Center (CHUL)

Curated by ChEMBL
LigandPNGBDBM17639((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...)copy SMILEScopy InChI
Affinity DataIC50: 90nMAssay Description:Inhibition of 17beta-HSD3 in rat testes microsomes using [14C]-4-androstene-3,17-dione as substrate after 2 hrsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20C4XHTPubMed
TargetG-protein coupled bile acid receptor 1(Homo sapiens (Human))
INSERM

Curated by ChEMBL
LigandPNGBDBM17639((1S,2S,5R,7S,10R,11S,15S)-5-hydroxy-2,15-dimethylt...)copy SMILEScopy InChI
Affinity DataEC50:  6.22E+3nMAssay Description:Agonist activity at human TGR5 expressed in CHO cells by luciferase assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2222VNJPubMed