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SMILES COc1c(O)ccc2OC(=Cc3sccc3C(C)N=O)c3c(ccc4NC(C)(C)C=C(C)c34)-c12

InChI Key InChIKey=VXOKHYHZXBLDSC-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 18622   

TargetGlucocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals Inc.

LigandPNGBDBM18622((18Z)-18-({3-[(1E)-1-(hydroxyimino)ethyl]thiophen-...)copy SMILEScopy InChI
Affinity DataKi:  0.600nM ΔG°:  -11.7kcal/mole IC50: 1.10nM EC50:  5nMpH: 7.5 T: 2°CAssay Description:Competitive Ligand Binding Assay- The Ki values were determined by the application of the Cheng-Prusoff equation: Ki=IC50/(1+[L]/Kd) where [L] is the...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T151XTPubMed
TargetMineralocorticoid receptor(Homo sapiens (Human))
Ligand Pharmaceuticals Inc.

LigandPNGBDBM18622((18Z)-18-({3-[(1E)-1-(hydroxyimino)ethyl]thiophen-...)copy SMILEScopy InChI
Affinity DataKi:  21nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T151XTPubMed
TargetAndrogen receptor(Homo sapiens (Human))
Ligand Pharmaceuticals Inc.

LigandPNGBDBM18622((18Z)-18-({3-[(1E)-1-(hydroxyimino)ethyl]thiophen-...)copy SMILEScopy InChI
Affinity DataKi:  290nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T151XTPubMed
TargetProgesterone receptor(Homo sapiens (Human))
Ligand Pharmaceuticals Inc.

LigandPNGBDBM18622((18Z)-18-({3-[(1E)-1-(hydroxyimino)ethyl]thiophen-...)copy SMILEScopy InChI
Affinity DataKi:  790nMAssay Description:The procedure for the cross reactivity receptor binding assays was using baculovirus-expressed receptors. After correcting for nonspecific binding, I...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T151XTPubMed