null

SMILES CCC#CC[C@H](C)[C@H](O)\C=C\[C@H]1CC(F)(F)C(=O)N1CCCc1ccc(s1)C(O)=O

InChI Key InChIKey=UMYXRXWDPHAKGZ-XLJJWPCRSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 190274   

TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical Company, Inc.

US Patent
LigandPNGBDBM190274(US9180116, 24D)copy SMILEScopy InChI
Affinity DataKi:  1.20nM IC50: 3.30nMpH: 6.0Assay Description:Assay Volume and Format:200 μl in 96-well plateCell membrane homogenates (20 μg protein) are incubated for 120 min at 22° C. with 0.5 nM [3...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC029SUS Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical Company, Inc.

US Patent
LigandPNGBDBM190274(US9180116, 24D)copy SMILEScopy InChI
Affinity DataEC50:  0.110nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC029SUS Patent
TargetProstaglandin E2 receptor EP2 subtype(Homo sapiens (Human))
Cayman Chemical Company, Inc.

US Patent
LigandPNGBDBM190274(US9180116, 24D)copy SMILEScopy InChI
Affinity DataEC50:  763nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 ul of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC029SUS Patent
TargetProstaglandin E2 receptor EP4 subtype(Homo sapiens (Human))
Cayman Chemical Company, Inc.

US Patent
LigandPNGBDBM190274(US9180116, 24D)copy SMILEScopy InChI
Affinity DataEC50:  0.730nMT: 2°CAssay Description:1. Seed cells on an EP2 or EP4 STEP plate at a density of 40,000-80,000 cells/well in 200 uL of reduced serum medium containing 0.5% FBS. Place the p...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QC029SUS Patent