null
SMILES Nc1nc(N)c2nc(c(N)nc2n1)-c1cccc(Cl)c1
InChI Key InChIKey=ZWNKKZSRANLVEW-UHFFFAOYSA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 8 hits for monomerid = 191572
TargetCasein kinase I isoform alpha(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 8.90E+3nMAssay Description:Single-point measurements analyses and subsequent dose-dependent investigations of selected pteridine derivatives for inhibition of CK1α were pe...More data for this Ligand-Target Pair
TargetCasein kinase I isoform delta(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 500nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
3D Structure (crystal)TargetCasein kinase I isoform epsilon(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 4.70E+3nMpH: 7.5Assay Description:A stock solution of 5 % DMSO (BioReagent for molecular biology, Sigma Aldrich) in water was prepared. The CK1 substrate peptide RRKDLHDDEEDEAMSITA (J...More data for this Ligand-Target Pair
TargetReceptor-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 3.81E+4nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
TargetEukaryotic elongation factor 2 kinase(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 2.74E+4nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
TargetEpidermal growth factor receptor [1-973](Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 8.30E+3nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
TargetMAP kinase-interacting serine/threonine-protein kinase 2(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 4.51E+4nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair
TargetSerine/threonine-protein kinase BRSK1(Homo sapiens (Human))
Max Planck Institute of Molecular Physiology
Max Planck Institute of Molecular Physiology
Affinity DataIC50: 2.42E+4nMAssay Description:Single-point measurement analyses of Epiblastin A against a panel of 123 kinases was performed at Eurofins (former Milipore) using a radiometric-base...More data for this Ligand-Target Pair