null

SMILES CC(=O)C(O)=O

InChI Key InChIKey=LCTONWCANYUPML-UHFFFAOYSA-N

PDB links: 242 PDB IDs match this monomer. 127 PDB IDs contain this monomer as substructures. 127 PDB IDs contain inhibitors having a similarity of 90% to this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 19473   

TargetMonocarboxylate transporter 2(Rattus norvegicus)
Physiologisch-chemisches Institut der Eberhard-Karls-Universit£t T£bingen

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)copy SMILEScopy InChI
Affinity DataKi:  8.00E+4nMAssay Description:TP_TRANSPORTER: inhibition of lactate uptake in Xenopus laevis oocytesMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2125TQVPubMed
TargetSolute carrier family 22 member 20(Mus musculus)
University of California

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)copy SMILEScopy InChI
Affinity DataKi:  2.71E+5nMAssay Description:Inhibition of mouse Oat6-mediated [3H]ES uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B35PubMed
TargetSolute carrier family 22 member 6(Mus musculus)
University of California

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)copy SMILEScopy InChI
Affinity DataKi:  1.19E+7nMAssay Description:Inhibition of mouse Oat1-mediated [3H]PAH uptake in Xenopus oocytes after 1 hrMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2W95B35PubMed
TargetSolute carrier organic anion transporter family member 2A1(Homo sapiens (Human))
Albert Einstein College of Medicine

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)copy SMILEScopy InChI
Affinity DataKi:  2.60E+7nMAssay Description:TP_TRANSPORTER: inhibition of PGE2 uptake in PGT-expressing HeLa cellsMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5G7CPubMedDrugBank
TargetProlyl 4-hydroxylase(Paramecium bursaria Chlorella virus 1)
University of Oxford

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of N-terminal His6-tagged recombinant Paramecium bursaria chlorella virus 1 CPH expressed in Escherichia coli Rosetta 2 (DE3) cells pre-in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2KK9G4RPubMed
TargetC-terminal-binding protein 2(Homo sapiens (Human))
Virginia Commonwealth University

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+5nMAssay Description:Inhibition of recombinant His6-tagged CtBP2 (31 to 384 residues) (unknown origin) dehydrogenase activity expressed in Escherichia coli BL21-Codonplus...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q28P62FXPubMed
TargetAlpha-ketoglutarate-dependent dioxygenase FTO(Homo sapiens (Human))
University of Oxford

Curated by ChEMBL
LigandPNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Inhibition of human hexahistidine-tagged full-length FTO expressed in Escherichia coli BL21 (DE3) using 3-methylthymidine as substrate assessed as in...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q21V5GBQPubMed

Activity Spreadsheet -- ITC Data from BindingDB

Found 2 hits for monomerid = 19473   

CellAcetate Operon Repressor (C-IclR)(Escherichia coli)
University of Toronto

SyringePNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
ITC DataΔG°: 7.20kcal/mole −TΔS°: 8.57kcal/mole ΔH°: -1.37kcal/mole logk: 6.40E+3
pH: 7.4 T: 25.00°C 
CellAcetate Operon Repressor (C-IclR)(Escherichia coli)
University of Toronto

SyringePNGBDBM19473(2-Oxopropanoate | 2-oxopropanoic acid | Pyruvate)
ITC DataΔH°: -5.79kcal/mole logk: 3.10E+3
pH: 7.4 T: 25.00°C