null

SMILES Cc1noc(C)c1-c1cc(c2nc(NCC3CC3)[nH]c2c1)S(=O)(=O)NC1CCCC1

InChI Key InChIKey=MEUUQDCOTOKHAT-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 249273   

TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM249273(US10017501, Compound 1020-1 | US9458145, 1020-1)copy SMILEScopy InChI
Affinity DataIC50: 201nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q1W53US Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Gilead Sciences Inc

US Patent
LigandPNGBDBM249273(US10017501, Compound 1020-1 | US9458145, 1020-1)copy SMILEScopy InChI
Affinity DataIC50: 97.6nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4M3ZUS Patent
TargetBromodomain-containing protein 4 [75-147](Homo sapiens (Human))
Gilead Sciences, Inc.

US Patent
LigandPNGBDBM249273(US10017501, Compound 1020-1 | US9458145, 1020-1)copy SMILEScopy InChI
Affinity DataIC50: 201nMAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CV4M3ZUS Patent
TargetBromodomain-containing protein 4 [368-440](Homo sapiens (Human))
Gilead Sciences Inc

US Patent
LigandPNGBDBM249273(US10017501, Compound 1020-1 | US9458145, 1020-1)copy SMILEScopy InChI
Affinity DataIC50: 97.6nMpH: 7.5 T: 2°CAssay Description:Binding of the two tandem bromodomains, BRD4-1 and BRD4-2, to an acetylated histone H4 peptide was measured using a homogeneous time resolved fluores...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26Q1W53US Patent