null
SMILES C[C@@H](N)COc1ccc2ncc(-c3cc4ccccc4o3)n2n1
InChI Key InChIKey=PHYSAVSMINAZFZ-LLVKDONJSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 259301
TargetGlutathione S-transferase P/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D](Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH
US Patent
BAYER INTELLECTUAL PROPERTY GMBH
US Patent
Affinity DataIC50: 43nMpH: 7.5 T: 2°CAssay Description:MKNK1-inhibitory activity at high ATP of compounds of the present invention after their preincubation with MKNK1 was quantified employing the TR-FRET...More data for this Ligand-Target Pair
TargetGlutathione S-transferase P/Isoform 2 of MAP kinase-interacting serine/threonine-protein kinase 1 (MNK1a) [T344D](Homo sapiens (Human))
BAYER INTELLECTUAL PROPERTY GMBH
US Patent
BAYER INTELLECTUAL PROPERTY GMBH
US Patent
Affinity DataIC50: 15nMpH: 7.5 T: 2°CAssay Description:A recombinant fusion protein of Glutathione-S-Transferase (GST, N-terminally) and human full-length MKNK1 (amino acids 1-424 and T344D of accession n...More data for this Ligand-Target Pair