null

SMILES Cc1ccc(cc1)-c1c(\C=C(/C#N)C(=O)OC(C)(C)C)n(CCCO)c2ncnc(N)c12

InChI Key InChIKey=IEUOMYJAIZIKES-SFQUDFHCSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 259806   

TargetRibosomal protein S6 kinase alpha-3 [399-740](Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

US Patent
LigandPNGBDBM259806(US9505766, CN-OtBu (5))copy SMILEScopy InChI
Affinity DataIC50: 7nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NPRUS Patent
TargetRibosomal protein S6 kinase alpha-3(Homo sapiens (Human))
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM259806(US9505766, CN-OtBu (5))copy SMILEScopy InChI
Affinity DataIC50: 7nMAssay Description:Inhibition of RSK2 in human MDA-MB-231 cells after 2 hrsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2JW8H9TPubMed
TargetRibosomal protein S6 kinase alpha-3 [399-740,C436V](Homo sapiens (Human))
THE REGENTS OF THE UNIVERSITY OF CALIFORNIA

US Patent
LigandPNGBDBM259806(US9505766, CN-OtBu (5))copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMpH: 8.0 T: 2°CAssay Description:RSK2 CTD and His6-ERK2 were expressed and purified as described (Cohen et al., Science, 308: 1318). The C436V mutant of RSK2 CTD was generated by Qui...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NPRUS Patent