null

SMILES CN1CCN(Cc2ccc(NC(=O)c3ccc(C)c(c3)C#Cc3nnc4cc(ccn34)C(N)=O)cc2C(F)(F)F)CC1

InChI Key InChIKey=LKFAYKJEZVDORL-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 260154   

TargetTyrosine-protein kinase ABL1 [T315I](Homo sapiens (Human))
OBSHCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYOU “FUSION PHARMA”

US Patent
LigandPNGBDBM260154(US9522910, Table 1 Compound 4: 3-{2-[2-methyl-5-({...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MHGUS Patent
TargetTyrosine-protein kinase ABL1(Homo sapiens (Human))
OBSHCHESTVO S OGRANICHENNOY OTVETSTVENNOSTYOU “FUSION PHARMA”

US Patent
LigandPNGBDBM260154(US9522910, Table 1 Compound 4: 3-{2-[2-methyl-5-({...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Kinase activity and inhibition was measured by established protocols (see e.g. Braunwalder et al., A Solid-Phase Assay for the Determination of Prote...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2542MHGUS Patent