null

SMILES CCN(CCO)CCCOc1cc2ncnc(Nc3cnn(CC(=O)Nc4cccc(F)c4)c3)c2cc1OC

InChI Key InChIKey=QFNBIMZYKKIEQO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 26306   

TargetAurora kinase B(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM26306(2-{4-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)copy SMILEScopy InChI
Affinity DataKi:  1nM ΔG°:  -12.1kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora B bound to INCENP was incubated at room temperature with substrate, and test compounds in the presence...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed
TargetAurora kinase A(Homo sapiens (Human))
AstraZeneca

LigandPNGBDBM26306(2-{4-[(7-{3-[ethyl(2-hydroxyethyl)amino]propoxy}-6...)copy SMILEScopy InChI
Affinity DataKi:  1.10E+3nM ΔG°:  -8.04kcal/molepH: 7.5 T: 2°CAssay Description:In vitro kinase assay using recombinant Aurora A purified from Sf9 cells was incubated at room temperature with substrate, and test compounds in the ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BZ64C7PubMed