null

SMILES COc1cccc(Cn2cnc(c2)-c2cc(ccn2)-c2c[nH]nn2)c1F

InChI Key InChIKey=TXLXRFMNSKJPLV-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 276068   

TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quanticel Research, Inc.

US Patent
LigandPNGBDBM276068(2-[1-[(2-fluoro-3-methoxyphenyl)methyl]imidazol-4-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X0XUS Patent
TargetHistone lysine demethylase PHF8(Homo sapiens (Human))
GSK

LigandPNGBDBM276068(2-[1-[(2-fluoro-3-methoxyphenyl)methyl]imidazol-4-...)copy SMILEScopy InChI
Affinity DataIC50: 300nMAssay Description:PHF8 Assay: The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction condit...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8PBQUS Patent
TargetLysine-specific demethylase 2B(Homo sapiens (Human))
Celgene Quanticel Research, Inc.

US Patent
LigandPNGBDBM276068(2-[1-[(2-fluoro-3-methoxyphenyl)methyl]imidazol-4-...)copy SMILEScopy InChI
Affinity DataIC50: 100nMAssay Description:The ability of test compounds to inhibit the activity of FBXL10 was determined in 384-well plate format under the following reaction conditions: 0.3 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2FT8PBQUS Patent
TargetIsoform 2 of Histone lysine demethylase PHF8 (2)(Homo sapiens (Human))
Celgene Quanticel Research, Inc.

US Patent
LigandPNGBDBM276068(2-[1-[(2-fluoro-3-methoxyphenyl)methyl]imidazol-4-...)copy SMILEScopy InChI
Affinity DataIC50: 550nMT: 2°CAssay Description:The ability of test compounds to inhibit the activity of PHF8 was determined in 384-well plate format under the following reaction conditions: 3 nM P...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24Q7X0XUS Patent