null

SMILES Nc1cccc2c(Cc3ccc(Br)c(Oc4cc(Cl)cc(c4)C#N)c3F)n[nH]c12

InChI Key InChIKey=GCEGOTUYYWDPTF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 27610   

TargetGag-Pol polyprotein [588-1027,K691N,Y769C]/[588-1147,K691N,Y769C](Human immunodeficiency virus type 1)
Roche Palo Alto LLC

LigandPNGBDBM27610(3-{3-[(7-amino-1H-indazol-3-yl)methyl]-6-bromo-2-f...)copy SMILEScopy InChI
Affinity DataIC50: 22nM EC50:  84nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed
TargetGag-Pol polyprotein [588-1027](Human immunodeficiency virus type 1 group M subtyp...)
Roche Palo Alto LLC

LigandPNGBDBM27610(3-{3-[(7-amino-1H-indazol-3-yl)methyl]-6-bromo-2-f...)copy SMILEScopy InChI
Affinity DataIC50: 24nM EC50:  8nMpH: 8.0 T: 2°CAssay Description:IC50s were obtained from the inhibition of the RNA-dependent DNA polymerase activity of the HIV-1 reverse transcriptase enzyme using a primer extensi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ5ZV0PubMed