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SMILES COC(=O)Nc1cc(ccn1)-c1ccc(OC[C@@](C)(N)CC(C)C)c(n1)C(F)F

InChI Key InChIKey=SVNVPNHWFJFRLZ-FQEVSTJZSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 311261   

TargetAP2-associated protein kinase 1(Mus musculus)TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataKi:  0.0700nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetTyrosine-protein kinase receptor TYRO3(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1.30E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2P55QWSUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2RF5XCXUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2Z60S4PUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2CF9T6JUS Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 0.800nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetBMP-2-inducible protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 20nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetDeath-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 560nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetCyclin-G-associated kinase(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 120nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetDeath-associated protein kinase 3(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetHomeodomain-interacting protein kinase 4(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 650nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 370nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetMyotonin-protein kinase(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 140nMMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TH8RSPPubMed
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2F191S4US Patent
TargetAP2-associated protein kinase 1(Homo sapiens (Human))
Bristol-Myers Squibb Co.

US Patent
LigandPNGBDBM311261((S)-methyl (5-((2-amino-2,4-dimethylpentyl)oxy)-6-...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2930WGGUS Patent