null
SMILES CCn1c2ccccc2c2cc(\C=N\Nc3cc(C)nc4cc5OCOc5cc34)ccc12
InChI Key InChIKey=ZXPGMLVLRGBYBF-MZJWZYIUSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 3 hits for monomerid = 318446
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh—Of the Commonwealth System of Higher Education
US Patent
University of Pittsburgh—Of the Commonwealth System of Higher Education
US Patent
Affinity DataKi: 120nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh—Of the Commonwealth System of Higher Education
US Patent
University of Pittsburgh—Of the Commonwealth System of Higher Education
US Patent
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of recombinant His-6 tagged human APE1 expressed in Escherichia coli C41(DE3) using 5'-(F)-CGACTXTTGAATTGACACGCCATGTCGATCAATTCAATAGTCG-(D)...More data for this Ligand-Target Pair
TargetDNA-(apurinic or apyrimidinic site) endonuclease(Homo sapiens (Human))
University of Pittsburgh—Of the Commonwealth System of Higher Education
US Patent
University of Pittsburgh—Of the Commonwealth System of Higher Education
US Patent
Affinity DataIC50: 4.10E+3nMAssay Description:The initial screen was designed to look at the effect of potential inhibitors on APE1 repair kinetics. The approach can be used as a high throughput ...More data for this Ligand-Target Pair