null

SMILES Clc1cccc(NC(=O)c2ccc(Br)o2)c1N1CCNCC1

InChI Key InChIKey=MRQHYUPABCEKKS-UHFFFAOYSA-N

PDB links: 1 PDB ID contains this monomer as substructures. 1 PDB ID contains inhibitors having a similarity of 90% to this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 32453   

TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM32453(piperazine amide, 4a)copy SMILEScopy InChI
Affinity DataIC50: 4.10E+3nMAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N67PubMed
TargetIsoform Alpha-1 of Mitogen-activated protein kinase 10 (Alpha-1) 9-402](Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM32453(piperazine amide, 4a)copy SMILEScopy InChI
Affinity DataIC50: 9.90E+3nMpH: 7.0 T: 2°CAssay Description:Biochemical IC50s for JNK were determined using HTRF. In each assay the phosphor-Thr71-ATF-2 product was detected using a Europium-cryptate labeled a...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2ST7N67PubMed