null

SMILES COc1ccc(cc1OCC1CC1)C(Cc1c(Cl)c[n+]([O-])cc1Cl)OC(=O)c1ccc(CNC(C(=O)OCC2CCN(C)CC2)c2cccc(O)c2)s1

InChI Key InChIKey=LXIIECIOHOQWLE-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 325653   

TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
CHIESI FARMACEUTICI S.p.A.

US Patent
LigandPNGBDBM325653(US9636336, Example 47 | US9636336, Example 48 | [1...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SH5US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)(Homo sapiens (Human))
CHIESI FARMACEUTICI S.p.A.

US Patent
LigandPNGBDBM325653(US9636336, Example 47 | US9636336, Example 48 | [1...)copy SMILEScopy InChI
Affinity DataIC50: 1nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SH5US Patent
TargetMuscarinic acetylcholine receptor M3(Homo sapiens (Human))
CHIESI FARMACEUTICI S.p.A.

US Patent
LigandPNGBDBM325653(US9636336, Example 47 | US9636336, Example 48 | [1...)copy SMILEScopy InChI
Affinity DataIC50: 55nMAssay Description:Human M3 receptor membranes (15 μg/well) from Perkin Elmer are incubated with 0.52 nM Scopolamine Methyl Chloride, [N-methyl-3H] with or without...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SH5US Patent
TargetIsoform PDE4B2 of cAMP-specific 3',5'-cyclic phosphodiesterase 4B (PDE4B2)(Homo sapiens (Human))
CHIESI FARMACEUTICI S.p.A.

US Patent
LigandPNGBDBM325653(US9636336, Example 47 | US9636336, Example 48 | [1...)copy SMILEScopy InChI
Affinity DataIC50: 5.5nMAssay Description:PDE4B2 activity is detected using the LANCE Ultra cAMP homogeneous time resolved fluorescence resonance energy transfer (TR-FRET) assay from Perkin E...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JS9SH5US Patent