null

SMILES Cc1cc(ccn1)-c1ccc(CC(=O)Nc2ccc(cc2)-c2ccccc2)cc1

InChI Key InChIKey=SNYVZWBGTUFKJH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 374846   

TargetProtein Wnt-3a(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM374846(US10251893, Cpd 50)copy SMILEScopy InChI
Affinity DataIC50: 0.240nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM89KJUS Patent
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374846(US10251893, Cpd 50)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374846(US10251893, Cpd 50)copy SMILEScopy InChI
Affinity DataIC50: 0.200nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed