null

SMILES CC(=O)N1CCN(CC1)c1ccc(NC(=O)Cc2cnc(c(C)c2)-c2ccnc(C)c2)nc1

InChI Key InChIKey=NEQNTAAQXJOQOM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 374948   

TargetProtein Wnt-3a(Homo sapiens (Human))
St. Jude Research Hospital

LigandPNGBDBM374948(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2',3...)copy SMILEScopy InChI
Affinity DataIC50: 1.60nMAssay Description:Human embryonic kidney 293 cells (obtained from American Type Culture Collection, ATCC, Manassas, Va.) are cultured in DMEM medium (Gibco/Invitrogen,...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2GM89KJUS Patent
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374948(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2',3...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed
TargetProtein-serine O-palmitoleoyltransferase porcupine(Mus musculus)
Genomics Institute of the Novartis Research Foundation

Curated by ChEMBL
LigandPNGBDBM374948(N-(5-(4-acetylpiperazin-1-yl)pyridin-2-yl)-2-(2',3...)copy SMILEScopy InChI
Affinity DataIC50: 0.700nMAssay Description:Inhibition of PORCN in mouse Leydig cells overexpressing Wnt3A co-cultured with TM3 cells transfected with Wnt-luciferase gene after 24 hrs by lumine...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FB56F9PubMed