null

SMILES Cc1cn(cn1)-c1cc(NC(=O)c2ccc(C)c(NC(=O)c3cncc(c3)-c3cccs3)c2)cc(c1)C(F)(F)F

InChI Key InChIKey=QASQEQBXMMXTAK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 375280   

TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375280(US10597387, Compound (I-3) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 196nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent
TargetTyrosine-protein kinase HCK(Homo sapiens (Human))
Dana-Farber Cancer Institute, Inc.

US Patent
LigandPNGBDBM375280(US10597387, Compound (I-3) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 62.2nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375280(US10597387, Compound (I-3) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 196nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2ZC85X9US Patent
TargetNuclear receptor subfamily 2 group C member 2(Homo sapiens (Human))
The Scripps Research Institute

LigandPNGBDBM375280(US10597387, Compound (I-3) | US9908872, Compound (...)copy SMILEScopy InChI
Affinity DataIC50: 62.2nMAssay Description:The in vitro activity of the compounds described herein in inhibiting TAK1, HCK, and other kinases were obtained using an Invitrogen Select Screening...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2668GH3US Patent