null

SMILES FC(F)(F)c1cnc(Nc2ccc3ncccc3c2)nc1NC1CC1

InChI Key InChIKey=GWRHBTXTQFLVSP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 379381   

TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM379381(N4-cyclopropyl-N2-(quinolin-6-yl)-5-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:Gamma-32P assays to measure ULK1 kinase activity were performed as previously described. Briefly, Flag ULK1 was transfected into HEK293T cells and 20...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2N30084US Patent
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM379381(N4-cyclopropyl-N2-(quinolin-6-yl)-5-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:ULK1 inhibition assay is a screening assay to identify compounds that inhibit kinase activity of ULK1 using the ULKtide peptide. In some embodiments,...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q24F1TTDUS Patent
TargetSerine/threonine-protein kinase ULK2(Homo sapiens (Human))TBA
LigandPNGBDBM379381(N4-cyclopropyl-N2-(quinolin-6-yl)-5-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 1.65E+3nMAssay Description:Inhibition of ULK2 (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3K0JPubMed
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM379381(N4-cyclopropyl-N2-(quinolin-6-yl)-5-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 739nMAssay Description:Inhibition of ULK1 (unknown origin) expressed in HEK293T cells incubated for 2 hrs by NanoBRET assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3K0JPubMed
TargetSerine/threonine-protein kinase ULK2(Homo sapiens (Human))TBA
LigandPNGBDBM379381(N4-cyclopropyl-N2-(quinolin-6-yl)-5-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 714nMAssay Description:Inhibition of recombinant human ULK2 (1 to 478 residues) expressed in Sf9 cells using myelin basic protein as substrate by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3K0JPubMed
TargetSerine/threonine-protein kinase ULK1(Homo sapiens (Human))
Berlex Biosciences

LigandPNGBDBM379381(N4-cyclopropyl-N2-(quinolin-6-yl)-5-(trifluorometh...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of recombinant human ULK1 (1-649) expressed in Sf9 cells using myelin basic protein as substrate by ADP-glo assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TX3K0JPubMed