null

SMILES CC[C@@H](Nc1c(Nc2cccc(c2O)S(C)(=O)=NC)c(=O)c1=O)c1ccccn1

InChI Key InChIKey=QZZHFDVECGMPIX-ICTCQJIBSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 385552   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385552(US10287278, Example 14 | US10287278, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028TWXUS Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385552(US10287278, Example 14 | US10287278, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028TWXUS Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385552(US10287278, Example 14 | US10287278, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028TWXUS Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385552(US10287278, Example 14 | US10287278, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1NM8US Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385552(US10287278, Example 14 | US10287278, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1NM8US Patent
TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385552(US10287278, Example 14 | US10287278, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1NM8US Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385552(US10287278, Example 14 | US10287278, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:To evaluate the direct interaction of the CXCR2 or CXCR1 receptor with β-arrestin 2, a test of β-arrestin 2 recruitment for CXCR2 or CXCR1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27H1NM8US Patent
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Universita degli Studi di Firenze

LigandPNGBDBM385552(US10287278, Example 14 | US10287278, Example 15 | ...)copy SMILEScopy InChI
Affinity DataIC50: 200nMAssay Description:The in vitro affinity of the compounds of the present invention for the CXCR1 and CXCR2 receptors is determined on a functional test of β-arrest...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2028TWXUS Patent