null

SMILES Cn1c(cc2ccc(cc12)-c1nccc(Nc2ccc3[nH]ncc3c2)n1)C(=O)Nc1ccnnc1

InChI Key InChIKey=IULQJJBCLQIQJM-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 399181   

TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amgen Inc.

LigandPNGBDBM399181(US10323023, Compound TDI01201 | US11390609, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q29C70S5US Patent
TargetRho-associated protein kinase 2(Homo sapiens (Human))
Amgen Inc.

LigandPNGBDBM399181(US10323023, Compound TDI01201 | US11390609, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9SM6US Patent
TargetRho-associated protein kinase 1(Homo sapiens (Human))TBA
LigandPNGBDBM399181(US10323023, Compound TDI01201 | US11390609, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 6.92E+3nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9SM6US Patent
TargetRho-associated protein kinase 2 [1-119](Homo sapiens (Human))
Vernalis (R&D) Ltd

LigandPNGBDBM399181(US10323023, Compound TDI01201 | US11390609, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 48nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q279471RUS Patent