null

SMILES CC(C)NC(=O)c1cc2ccc(cc2[nH]1)-c1nccc(Nc2ccc3[nH]ncc3c2)n1

InChI Key InChIKey=FVFVXEKERCCCOH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 402298   

TargetRho-associated protein kinase 2(Homo sapiens (Human))TBA
LigandPNGBDBM402298(US10329282, Compound TDI01108 | US11390609, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20R9SM6US Patent
TargetRho-associated protein kinase 2 [1-119](Homo sapiens (Human))
Vernalis (R&D) Ltd

LigandPNGBDBM402298(US10329282, Compound TDI01108 | US11390609, Compou...)copy SMILEScopy InChI
Affinity DataIC50: 22nMAssay Description:The kinase IC50 was determined by a commercialized CISBIO kinase detection kit, HTRF KinEASE-STK S2 kit (62ST2PEC). ROCK2 (01-119) employed in the re...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q279471RUS Patent