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SMILES C[C@H]1CN(CCN1Cc1ccc2c3NCCCc3c(=O)[nH]c2c1)c1ccc(C#N)c(F)c1

InChI Key

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 419775   

TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
Je Il Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM419775(US10464919, Example 113)copy SMILES
Affinity DataIC50: 10.3nMAssay Description:The PARP-1 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of a kit (cat. 80551) p...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736T8MUS Patent
TargetActivated CDC42 kinase 1(Homo sapiens (Human))
Je Il Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM419775(US10464919, Example 113)copy SMILES
Affinity DataIC50: 3.49nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736T8MUS Patent
TargetNon-receptor tyrosine-protein kinase TNK1(Homo sapiens (Human))
Je Il Pharmaceutical Co., Ltd.

US Patent
LigandPNGBDBM419775(US10464919, Example 113)copy SMILES
Affinity DataIC50: 10.7nMAssay Description:The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2736T8MUS Patent