null

SMILES CC(C)C[C@H](NC(=O)c1nc2ccccc2[nH]1)C(=O)N[C@@H](C[C@@H]1CCNC1=O)C=O

InChI Key InChIKey=CQAHVFTUINWYCR-ZQIUZPCESA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 423464   

TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer Inc.

LigandPNGBDBM423464(WO2006061714, P38.7 | WO2006061714-ID-09 | cmdc.20...)copy SMILEScopy InChI
Affinity DataIC50: 32nMAssay Description:The SARS 3CLpro FRET assay measures the protease catalyzed cleavage of TAMRA- SITSAVLQSGFRKMK-(DABCYL)-OH to TAMRA - SITSAVLQ and SGFRKMK- (DABCYL)-O...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6NRFPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer Inc.

LigandPNGBDBM423464(WO2006061714, P38.7 | WO2006061714-ID-09 | cmdc.20...)copy SMILEScopy InChI
Affinity DataIC50: 30nMAssay Description:Please point to the patents.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q27M0C3WPubMed
TargetReplicase polyprotein 1ab(SARS coronavirus Urbani)
Pfizer Inc.

LigandPNGBDBM423464(WO2006061714, P38.7 | WO2006061714-ID-09 | cmdc.20...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+4nM EC50:  3.60E+6nMAssay Description:Proteolytic activity of Coronavirus 3C protease is measured using a continuous fluorescence resonance energy transfer assay. The SARS 3CI_pro FRET as...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q22V2K5WPubMed
TargetReplicase polyprotein 1ab(Human SARS coronavirus (SARS-CoV) (Severe acute re...)
Pfizer Inc.

LigandPNGBDBM423464(WO2006061714, P38.7 | WO2006061714-ID-09 | cmdc.20...)copy SMILEScopy InChI
Affinity DataEC50:  3.60E+3nMAssay Description:Protection from SARS Infection: Neutral Red Endpoint The ability of compounds to protect cells against infection by the SARS coronavirus is measured ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2PV6NRFPubMed