null

SMILES CNc1nc(NC2C3CCC2CN(C3)c2ccnc(OC)c2)nc2N(CC(C)(C)c12)c1cccc(F)c1F

InChI Key InChIKey=BMKDGRHSZVIMOJ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 455364   

TargetAmyloid-beta precursor protein(Homo sapiens (Human))
HOFFMANN-LA ROCHE, INC.

US Patent
LigandPNGBDBM455364(7-(2,3-Difluorophenyl)-N4,5,5-trimethyl-N2-((1R,5S...)copy SMILEScopy InChI
Affinity DataEC50:  10nMAssay Description:Human neuroglioma H4 cells overexpressing human APP695 with the Swedish double mutation (K595N/M596L) were plated at 30,000 cells/well/100 μl in...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q27M0C0JUS Patent