null

SMILES C=CC(=O)N1CC[C@@]2(C[C@@H](C2)n2c(NC(=O)c3ccc(s3)-c3ccnnc3)nc3ccccc23)C1

InChI Key InChIKey=KNEKVQSXRQKRBO-AJHAWQTOSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 458216   

TargetTyrosine-protein kinase ITK/TSK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458216(US10752615, Compound 114)copy SMILEScopy InChI
Affinity DataIC50: 1.28nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase Tec(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458216(US10752615, Compound 114)copy SMILEScopy InChI
Affinity DataIC50: 0.230nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase BTK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458216(US10752615, Compound 114)copy SMILEScopy InChI
Affinity DataIC50: 3.31nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent
TargetTyrosine-protein kinase TXK(Homo sapiens (Human))
GB005, Inc.

US Patent
LigandPNGBDBM458216(US10752615, Compound 114)copy SMILEScopy InChI
Affinity DataIC50: 0.220nMAssay Description:The in vitro kinase assays were performed at Nanosyn (Santa Clara, Calif.) utilizing microfluidic detection technology. The test compounds were seria...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G163WGUS Patent