null

SMILES OC(=O)COc1ccc(CCNS(=O)(=O)c2ccccc2)cc1

InChI Key InChIKey=XTNWJMVJVSGKLR-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 8 hits for monomerid = 50002765   

TargetThromboxane A2 receptor(Homo sapiens (Human))
Carpibem

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...)copy SMILEScopy InChI
Affinity DataKi:  650nMAssay Description:Tested in vitro for inhibition constant against TXA2 / PGH-2 receptor using [125I]-PTA-OH binding affinity to human plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2R49PT8PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Carpibem

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of the thromboxane A2 receptor assayed by binding to guinea pig platelets using [3H]-U-46,619 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SV5PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Carpibem

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...)copy SMILEScopy InChI
Affinity DataKi:  1.30E+3nMAssay Description:Inhibition of the thromboxane A2 receptor assayed by binding to guinea pig platelets using [3H]-U-46,619 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SV5PubMed
TargetThromboxane A2 receptor(Homo sapiens (Human))
Carpibem

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...)copy SMILEScopy InChI
Affinity DataKi:  1.40E+3nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2D21W4ZPubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory effect of the compound against thromboxane A2 synthase binding to bovine plateletsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SV5PubMed
TargetThromboxane-A synthase(Rattus norvegicus)
Kyowa Hakko Kogyo Company, Ltd.

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of the thromboxane A2 receptor assayed by binding to guinea pig platelets using [3H]-U-46,619 as radioligandMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2NS0SV5PubMed
TargetThromboxane-A synthase(Homo sapiens (Human))
Kyowa Hakko Kogyo Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...)copy SMILEScopy InChI
Affinity DataIC50: 9.41E+4nMAssay Description:Activity against TXA2 synthase in bovine platelet microsomeMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2639NTJPubMed
TargetThromboxane A2 receptor(RAT)
TBA

Curated by ChEMBL
LigandPNGBDBM50002765(BM 13177 | BM-13177 | CHEMBL8273 | Sulotroban | [4...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Tested for antagonistic activity on isolated rat thoracic aorta (thromboxane A2 receptor) precontracted by U-46619 (3 x 10 e-8 M)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2H70FQG