null

SMILES O=C(Nc1nccs1)C1C(=O)N2c3c1cccc3Oc1ccccc21

InChI Key InChIKey=CVSIFFANCIQNKO-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50012860   

TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50012860(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:In vitro inhibition of 5-lipoxygenase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73F9XPubMed
TargetProstaglandin G/H synthase 1(RAT)
University of Calabria

Curated by ChEMBL
LigandPNGBDBM50012860(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+3nMAssay Description:Inhibition of cyclooxygenase-1 in rat RBL-1 cells preincubated for 10 mins followed by [14C]arachidonic acid addition and measured after 5 mins by ra...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5C4QPubMed
TargetPolyunsaturated fatty acid 5-lipoxygenase(Rattus norvegicus)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50012860(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of 5-lipoxygenase in rat RBL-1 cells preincubated for 10 mins followed by [14C]arachidonic acid addition and measured after 5 mins by radi...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2HM5C4QPubMed
TargetProstaglandin G/H synthase 1/2(RAT)
Pfizer Central Research

Curated by ChEMBL
LigandPNGBDBM50012860(1-Oxo-1,2-dihydro-6-oxa-10b-aza-aceanthrylene-2-ca...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Prostaglandin G/H synthase pathway in rat basophilic leukemia (RBL-1) cellsMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2G73F9XPubMed