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SMILES NC(C(O)=O)c1ccc(C(O)=O)c(O)c1

InChI Key InChIKey=GXZSAQLJWLCLOX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 14 hits for monomerid = 50030628   

TargetMetabotropic glutamate receptor 1(RAT)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi:  1.65nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7F62PubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi:  2.50E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J67FGZPubMed
TargetMetabotropic glutamate receptor 5(Homo sapiens (Human))
F. Hoffmann-La Roche

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
UPR Centre

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2M61HS5PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
UPR Centre

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2M043ZHPubMed
TargetMetabotropic glutamate receptor 1(RAT)
Johnson and Johnson Pharmaceutical Research and Development, Beerse

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2BV7F62PubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
UPR Centre

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi:  2.00E+4nMAssay Description:Agonist potency against cloned Metabotropic glutamate receptor 2 (mGluR-2).More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi:  3.00E+4nMAssay Description:Agonist potency against cloned human metabotropic glutamate receptor 1More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataKi: >1.00E+6nMAssay Description:Agonist potency against cloned human Metabotropic glutamate receptor 4 (mGluR-4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2DZ090QPubMed
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+5nMAssay Description:Compound was tested for inhibition of glutamate-evoked (10 uM) [Ca2+] mobilization in mGluR1-alpha expressed-CHO cells.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WS8T7Q
TargetMetabotropic glutamate receptor 1(Homo sapiens (Human))
Emory University

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 4.00E+4nMAssay Description:Ability to inhibit mGluR1-alpha-mediated PI (phospho inosotol) hydrolysis was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123TGPubMed
TargetMetabotropic glutamate receptor 2(Homo sapiens (Human))
UPR Centre

Curated by PDSP Ki Database
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 4.80E+4nMAssay Description:Ability to inhibit mGluR2-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123TGPubMed
TargetMetabotropic glutamate receptor 4(Homo sapiens (Human))
The Royal Danish School of Pharmacy

Curated by ChEMBL
LigandPNGBDBM50030628((S)-4C3HPG | 4-(Amino-carboxy-methyl)-2-hydroxy-be...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+6nMAssay Description:Ability to inhibit mGluR4-alpha induced cAMP formation was determined at BHK cells at 100 Micro M ConcentrationMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2V123TGPubMed