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SMILES O=C1N(CCCCCCN2CCN(CC2)c2nsc3ccccc23)C(=O)c2ccccc12

InChI Key InChIKey=ZWXUIJOENHRFLU-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50048817   

TargetD(2) dopamine receptor(Homo sapiens (Human))
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50048817(2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-he...)copy SMILEScopy InChI
Affinity DataKi:  10nMAssay Description:Displacement of [3H]-raclopride from human D2L receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RJBPubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50048817(2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-he...)copy SMILEScopy InChI
Affinity DataKi:  18nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5HT1A receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RJBPubMed
Target5-hydroxytryptamine receptor 2A(Homo sapiens (Human))
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50048817(2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-he...)copy SMILEScopy InChI
Affinity DataKi:  24nMAssay Description:Displacement of [3H]-ketanserin from recombinant human 5HT2A receptor expressed in CHOK1 cell membranes measured after 1 hr by microbeta counting met...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RJBPubMed
Target5-hydroxytryptamine receptor 7(Homo sapiens (Human))
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50048817(2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-he...)copy SMILEScopy InChI
Affinity DataKi:  114nMAssay Description:Displacement of [3H]-5-CT from human 5HT7b receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RJBPubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Cracow University of Technology

Curated by ChEMBL
LigandPNGBDBM50048817(2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-he...)copy SMILEScopy InChI
Affinity DataKi:  160nMAssay Description:Displacement of [3H]-LSD from human 5HT6 receptor expressed in HEK293 cell membranes measured after 1 hr by microbeta counting methodMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2D50RJBPubMed
TargetD(2) dopamine receptor(Rattus norvegicus (rat))
Glaxo Wellcome Inc.

Curated by ChEMBL
LigandPNGBDBM50048817(2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-he...)copy SMILEScopy InChI
Affinity DataIC50: 9.20nMAssay Description:Inhibition of [3H]-raclopride binding at Dopamine receptor D2 from rat striata.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ60MNPubMed
Target5-hydroxytryptamine receptor 1A(Rattus norvegicus (rat))
Glaxo Wellcome Inc.

Curated by ChEMBL
LigandPNGBDBM50048817(2-[6-(4-Benzo[d]isothiazol-3-yl-piperazin-1-yl)-he...)copy SMILEScopy InChI
Affinity DataIC50: 0.760nMAssay Description:Inhibition of [3H]-8-OH-DPAT binding at serotonin 5-hydroxytryptamine 1A receptor from rat hippocampus tissue.More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2TQ60MNPubMed