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SMILES COC(=O)N[C@@H](C(C)C)C(=O)N1CCC[C@H]1C(=O)N[C@@H](C(C)C)C(=O)C(F)(F)F

InChI Key InChIKey=ZYLBZJKJNAYAFU-AVGNSLFASA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50061024   

TargetChymotrypsin-like elastase family member 2A(Sus scrofa)
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061024((2-Methyl-1-{(S)-oxo-[(S)-2-((S)-3,3,3-trifluoro-1...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Binding affinity of the compound for porcine Pancreatic elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5M85PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50061024((2-Methyl-1-{(S)-oxo-[(S)-2-((S)-3,3,3-trifluoro-1...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:oral activity of the compoundChecked by AuthorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2JD4XH4PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50061024((2-Methyl-1-{(S)-oxo-[(S)-2-((S)-3,3,3-trifluoro-1...)copy SMILEScopy InChI
Affinity DataKi:  13nMAssay Description:Binding affinity for human leukocyte elastaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5M85PubMed
TargetChymotrypsin-C(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061024((2-Methyl-1-{(S)-oxo-[(S)-2-((S)-3,3,3-trifluoro-1...)copy SMILEScopy InChI
Affinity DataKi:  149nMAssay Description:Binding affinity of the compound for human pancreatic ChymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5M85PubMed
TargetSerine protease 1(Homo sapiens (Human))
ZENECA Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50061024((2-Methyl-1-{(S)-oxo-[(S)-2-((S)-3,3,3-trifluoro-1...)copy SMILEScopy InChI
Affinity DataKi:  6.66E+4nMAssay Description:Binding affinity of the compound for human pancreatic trypsinMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5M85PubMed
TargetNeutrophil elastase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50061024((2-Methyl-1-{(S)-oxo-[(S)-2-((S)-3,3,3-trifluoro-1...)copy SMILEScopy InChI
Affinity DataIC50: 135nMMore data for this Ligand-Target Pair
In DepthDetails
TargetNeutrophil elastase(Homo sapiens (Human))
University of Queensland

Curated by ChEMBL
LigandPNGBDBM50061024((2-Methyl-1-{(S)-oxo-[(S)-2-((S)-3,3,3-trifluoro-1...)copy SMILEScopy InChI
Affinity DataIC50: 10nMAssay Description:In vitro inhibitory activity in human whole blood (HWB) elastaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2K074SHPubMed