null

SMILES CC(C)(C)c1cc(\C=C2/C(=O)Nc3ccccc23)cc(c1O)C(C)(C)C

InChI Key InChIKey=NUMNJHZZSGKINB-WJDWOHSUSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50065275   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065275(3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...)copy SMILEScopy InChI
Affinity DataIC50: 6.48E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065275(3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065275(3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...)copy SMILEScopy InChI
Affinity DataIC50: 6.50E+4nMAssay Description:Inhibition of HER2 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2086532PubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065275(3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...)copy SMILEScopy InChI
Affinity DataIC50: 4.95E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed
TargetVascular endothelial growth factor receptor 1(Mus musculus)
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065275(3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...)copy SMILEScopy InChI
Affinity DataIC50: 8.40E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065275(3-(3,5-di-tert-butyl-4-hydroxybenzylidene)indolin-...)copy SMILEScopy InChI
Affinity DataIC50: 7.90E+3nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed