null

SMILES Cc1ccc(\C=C2\C(=O)Nc3ccccc23)o1

InChI Key InChIKey=DWJWWZSAYOTJGO-XYOKQWHBSA-N

PDB links: 1 PDB ID matches this monomer.

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50065309   

LigandPNGBDBM50065309(3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol...)copy SMILEScopy InChI
Affinity DataKi:  4.40E+3nMAssay Description:Binding affinity to DYRK1A (unknown origin) assessed as inhibition constant by ADP hunter plus assayMore data for this Ligand-Target Pair
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065309(3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Her-2 receptor tyrosine kinase (HER-2 RTK)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed
TargetPlatelet-derived growth factor receptor beta(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065309(3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Test concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Platelet-derived growth factor receptor beta (PDGF RTK).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed
TargetInsulin-like growth factor 1 receptor(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065309(3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Insulin-like growth factor I receptorMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed
TargetVascular endothelial growth factor receptor 1(Mus musculus)
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065309(3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol...)copy SMILEScopy InChI
Affinity DataIC50: 7.36E+4nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on murine VEGF receptor (FLK-1 RTK).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed
TargetVascular endothelial growth factor receptor 2(Mus musculus)
Eli Lilly and Company

Curated by ChEMBL
LigandPNGBDBM50065309(3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol...)copy SMILEScopy InChI
Affinity DataIC50: 7.41E+4nMAssay Description:Inhibitory activity against vascular endothelial growth factor receptor 2 (FLK1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2HM59P2PubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
SUGEN, Inc.

Curated by ChEMBL
LigandPNGBDBM50065309(3-(5-Methyl-furan-2-ylmethylene)-1,3-dihydro-indol...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Concentration required to achieve 50% inhibition of tyrosine phosphorylation on human Epidermal growth factor receptor (EGF RTK).More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2G73CTTPubMed