null

SMILES CC(C)c1ccc(cc1)S(=O)(=O)Nc1cc(Sc2nc[nH]n2)c(O)c2ccccc12

InChI Key InChIKey=MFEOAVQPFYZKIH-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 12 hits for monomerid = 50076479   

TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataKi:  7.10E+4nMAssay Description:Inhibition of Cys5-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measu...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9SSFPubMed
TargetHistone acetyltransferase GCN5(Saccharomyces cerevisiae S288c)
Mayo Clinic College of Medicine

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataIC50: 5.10E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M38J9PubMed
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataEC50:  2.90E+3nMAssay Description:Inhibition of Keap1 (unknown origin) interaction to Nrf2More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2FN181BPubMed
TargetNuclear factor erythroid 2-related factor 2(Homo sapiens (Human))
University College London

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataKd:  2.90E+3nMAssay Description:Inhibition of Keap1-Nrf2 (unknown origin) interaction assessed as compound's equilibrium dissociation constant after 60 mins by fluorescence anisotro...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q261139GPubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataKd:  3.60E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataKd: >5.00E+5nMAssay Description:Binding affinity to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) by surface plasmon resonance ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9SSFPubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FAM-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9SSFPubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataKd:  2.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2F193RHPubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataIC50: 2.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2T157QMPubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataKd:  2.90E+3nMMore data for this Ligand-Target Pair
In DepthDetails
TargetHistone acetyltransferase GCN5(Saccharomyces cerevisiae S288c)
Mayo Clinic College of Medicine

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of Vps75-stimulated recombinant Saccharomyces cerevisiae histone acetyltransferase Rtt109 using Asf1-dH3-H4 as substrate assessed as coenz...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q26M38J9PubMed
TargetKelch-like ECH-associated protein 1(Homo sapiens (Human))
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50076479(CHEMBL3235901)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of FAM-LDEETGEFL-NH2 binding to recombinant human KEAP1 Kelch domain (321 to 609 residues) expressed in Escherichia coli BL21 (DE3) measur...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q20R9SSFPubMed