null
SMILES CCCCCCCCCCCCCCCC1=C(OC)C(=O)C=C(OC)C1=O
InChI Key InChIKey=PTLFMJIEUCESBJ-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50078869
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 390nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation pre-incubated for 15 mins followed...More data for this Ligand-Target Pair
TargetMacrophage-expressed gene 1 protein(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 7.20E+3nMAssay Description:Inhibition of mPGES1 in IL-1beta stimulated human A549 cell microsomal membranes assessed as reduction in PGE2 synthase activity after 15 mins using ...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 860nMAssay Description:Inhibition of 5-LOX in A23187-stimulated human blood PMNL assessed as reduction in lipoxygenase products formation in presence of arachidonic acid pr...More data for this Ligand-Target Pair
TargetPolyunsaturated fatty acid 5-lipoxygenase(Homo sapiens (Human))
University of Naples
Curated by ChEMBL
University of Naples
Curated by ChEMBL
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant 5-LOX expressed in Escherichia coli BL21 incubated for 10 mins in presence of arachidonic acid by RP-HPLC based cell-...More data for this Ligand-Target Pair