null

SMILES Fc1ccccc1C(=O)Nc1ccc-2c(c1)C(=O)C(=O)c1ccccc-21

InChI Key InChIKey=BYGWCJMXSGBHQK-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50099713   

TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory concentration against FAP-1 using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed
TargetProcathepsin L(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 400nMAssay Description:Inhibitory concentration against Cathepsin LMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase using lck-10 mer as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against CD45 protein-tyrosine phosphatase pNPPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed
TargetTyrosine-protein phosphatase non-receptor type 13(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against FAP-1 pNPPMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed
TargetCathepsin S(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibitory concentration against Cathepsin SMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed
TargetCathepsin B(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory concentration against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed
TargetTyrosine-protein phosphatase non-receptor type 1(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory concentration against PTP1B using lck as substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed
TargetReceptor-type tyrosine-protein phosphatase C(Homo sapiens (Human))
AstraZeneca Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50099713(CHEMBL50878 | N-(9,10-Dioxo-9,10-dihydro-phenanthr...)copy SMILEScopy InChI
Affinity DataIC50: 600nMAssay Description:In vitro inhibitory activity against the cytosolic portion of CD45 protein-tyrosine phosphatase using pNPP as the substrateMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2X34WQQPubMed