null

SMILES COC(=O)c1c(-c2cc(OC)c(OC)c(OC)c2)c2ccc(OCc3ccncc3)cc2c(=O)n1-c1ccc(N)cc1

InChI Key InChIKey=PXMVFFZDJQCKOX-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50100670   

TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4A/4B/4C/4D(Homo sapiens (Human))
Tanabe Seiyaku Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50100670(CHEMBL553786 | methyl 2-(4-aminophenyl)-1-oxo-7-(4...)copy SMILEScopy InChI
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of canine lung Phosphodiesterase 4 (PDE4)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4XT5PubMed
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
Tanabe Seiyaku Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50100670(CHEMBL553786 | methyl 2-(4-aminophenyl)-1-oxo-7-(4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory activity against canine heart Phosphodiesterase 3 (PDE3)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4XT5PubMed
TargetcGMP-dependent 3',5'-cyclic phosphodiesterase(Bos taurus)
Tanabe Seiyaku Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50100670(CHEMBL553786 | methyl 2-(4-aminophenyl)-1-oxo-7-(4...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of bovine adrenal gland Phosphodiesterase 2 (PDE2)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4XT5PubMed
LigandPNGBDBM50100670(CHEMBL553786 | methyl 2-(4-aminophenyl)-1-oxo-7-(4...)copy SMILEScopy InChI
Affinity DataIC50: 9.50E+3nMAssay Description:Inhibitory activity against rat heart Phosphodiesterase 1(PDE1)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4XT5PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Canis lupus familiaris)
Tanabe Seiyaku Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50100670(CHEMBL553786 | methyl 2-(4-aminophenyl)-1-oxo-7-(4...)copy SMILEScopy InChI
Affinity DataIC50: 3.10nMAssay Description:Inhibitory activity against canine lung Phosphodiesterase 5 (PDE5)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4XT5PubMed
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Tanabe Seiyaku Co., Ltd.

Curated by ChEMBL
LigandPNGBDBM50100670(CHEMBL553786 | methyl 2-(4-aminophenyl)-1-oxo-7-(4...)copy SMILEScopy InChI
Affinity DataEC50:  12nMAssay Description:Relaxant effect on isolated rabbit corpus cavernosumMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2QR4XT5PubMed