null
SMILES COc1nccc(n1)-c1c(ncn1[C@H]1CC[C@H](O)CC1)-c1ccc(F)cc1
InChI Key InChIKey=ZQUSFAUAYSEREK-WKILWMFISA-N
PDB links: 1 PDB ID matches this monomer.
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 18 hits for monomerid = 50105742
TargetMitogen-activated protein kinase 9(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5nMAssay Description:Inhibition of JNK2beta2 kinaseMore data for this Ligand-Target Pair
TargetEpidermal growth factor receptor(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of cRaf kinaseMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 18nMAssay Description:Inhibition of p56 Lck kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 8(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of JNK1 kinaseMore data for this Ligand-Target Pair
TargetDual specificity mitogen-activated protein kinase kinase 2(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of ERK2 kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of p38alphaChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 44nMAssay Description:Inhibition of p38-beta MAP kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 12(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38-gamma MAP kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 13(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of p38delta MAP kinaseChecked by AuthorMore data for this Ligand-Target Pair
TargetRAF proto-oncogene serine/threonine-protein kinase(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of Raf1 kinaseMore data for this Ligand-Target Pair
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
TargetMitogen-activated protein kinase 11(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
University of Oxford
Curated by ChEMBL
University of Oxford
Curated by ChEMBL
Affinity DataIC50: 34nMAssay Description:Inhibition against Mitogen-activated protein kinase p38 alphaMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 83nMAssay Description:Inhibition of PKCalpha kinaseMore data for this Ligand-Target Pair
TargetCyclin-dependent kinase 1(Homo sapiens (Human))
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
GlaxoSmithKline Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 50nMAssay Description:Inhibition of cdc2 kinaseMore data for this Ligand-Target Pair