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SMILES Oc1ccc(cc1O)-c1csc(Nc2ccc(F)cc2F)n1

InChI Key InChIKey=GFUKFZXSGYDXIF-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50111591   

TargetBeta-galactosidase(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 3.20E+5nMAssay Description:Inhibition of Beta-galactosidaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WHDPubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against beta-lactamaseMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WHDPubMed
TargetDihydrofolate reductase(Gallus gallus (Chicken))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.50E+5nMAssay Description:Inhibitory activity against cloned Dihydrofolate reductase (cDHFR)More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WHDPubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.33E+5nMAssay Description:Inhibitory activity against beta-lactamase in the presence of 500 mMKPi concentration of bufferMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WHDPubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against Amp C beta-LactamaseMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q29C6Z59PubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory activity against beta-lactamase in the presence of 5 mM KPi concentration of bufferMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WHDPubMed
TargetChymotrypsin-C(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against chymotrypsinogenMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WHDPubMed
TargetMalate dehydrogenase(Thermus thermophilus)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 2.50E+4nMAssay Description:Inhibitory activity against malate dehydrogenase (MDH) from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78FZTPubMed
TargetChymotrypsinogen B(Homo sapiens (Human))
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory activity against Chymotrypsinogen from Thermus flavusMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2R78FZTPubMed
TargetBeta-lactamase(Escherichia coli)
Northwestern University

Curated by ChEMBL
LigandPNGBDBM50111591(4-[2-(2,4-Difluoro-phenylamino)-thiazol-4-yl]-benz...)copy SMILEScopy InChI
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibitory activity against beta-lactamase in the presence of 50 mM KPi concentration of bufferMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q20C4WHDPubMed