null

SMILES Oc1ccc(Oc2c(Cl)cc(cc2Cl)-n2ncc(=O)[nH]c2=O)cc1C(=O)N1CCCCC1

InChI Key InChIKey=KQTUYIZQBZEKGQ-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50123049   

TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123049(2-(3,5-dichloro-4-(4-hydroxy-3-(piperidine-1-carbo...)copy SMILEScopy InChI
Affinity DataKi:  0.630nMAssay Description:Inhibitory activity against [125I]-T3 binding to human TRbeta1 receptorMore data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q26T0KZBPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123049(2-(3,5-dichloro-4-(4-hydroxy-3-(piperidine-1-carbo...)copy SMILEScopy InChI
Affinity DataKi:  1nMAssay Description:Binding affinity to thyroid receptor betaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SNPPubMed
TargetThyroid hormone receptor alpha(Homo sapiens (Human))
Pfizer Global Research& Development

Curated by ChEMBL
LigandPNGBDBM50123049(2-(3,5-dichloro-4-(4-hydroxy-3-(piperidine-1-carbo...)copy SMILEScopy InChI
Affinity DataKi:  20nMAssay Description:Binding affinity to thyroid receptor alphaMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2J38SNPPubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123049(2-(3,5-dichloro-4-(4-hydroxy-3-(piperidine-1-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.74nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HD8PubMed
TargetThyroid hormone receptor beta(Homo sapiens (Human))
Pfizer Global Research and Development

Curated by ChEMBL
LigandPNGBDBM50123049(2-(3,5-dichloro-4-(4-hydroxy-3-(piperidine-1-carbo...)copy SMILEScopy InChI
Affinity DataIC50: 1.74nMAssay Description:Inhibition of human thyroid hormone receptor beta 1More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2PK0HD8PubMed