null

SMILES COc1ccc(Cl)cc1-c1cc(=O)[nH]c(=S)n1CC(N)=O

InChI Key InChIKey=ICYNYWFGIDGBRD-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 19 hits for monomerid = 50133595   

TargetMyeloperoxidase(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataKi:  316nMAssay Description:Inhibition of peroxidase activity of MPO isolated from human polynuclear leukocytes using Amplex Red as substrate assessed as formation of resorufin ...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.90E+3nMAssay Description:Irreversible inhibition of MPO in LPS-stimulated human whole blood after 4 hrs by Amplex Red/H2O2-based fluorescence plate reader analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Reversible inhibition of CYP1A2 phenacetin O-deethylase activity in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Reversible inhibition of CYP2B6 bupropion hydroxylase activity in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Reversible inhibition of CYP2C8 amodiaquine-N-deethylase activity in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Reversible inhibition of CYP2C9 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Reversible inhibition of CYP2C19 (S)-Mephenytoin 4'-hydroxylase activity in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Reversible inhibition of CYP2D6 dextromethorphan O-demethylase activity in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetThyroid peroxidase(Homo sapiens (Human))TBA
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 990nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44KMPubMed
TargetCytochrome P450 1A2(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Time-dependent inhibition of CYP1A2 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2B6(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Time-dependent inhibition of CYP2B6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2C8(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Time-dependent inhibition of CYP2C8 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2C9(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Time-dependent inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2C19(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Time-dependent inhibition of CYP2C19 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 2D6(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Time-dependent inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 187nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44KMPubMed
TargetMyeloperoxidase(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 3.55E+4nMMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2WD44KMPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Time-dependent inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed
TargetCytochrome P450 3A4(Homo sapiens (Human))
Pfizer Inc.

Curated by ChEMBL
LigandPNGBDBM50133595(CHEMBL3633460)copy SMILEScopy InChI
Affinity DataIC50: 1.00E+5nMAssay Description:Reversible inhibition of CYP3A4 in human liver microsomes by LC-MS/MS analysisMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2SQ926XPubMed