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SMILES CCOc1ccc2cc(cnc2c1)-c1nn(C(C)CCO)c(N)c1C(N)=O

InChI Key InChIKey=CKYKSFPZSGEXCP-UHFFFAOYSA-N

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50148647   

TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148647(CHEMBL3769570 | US9518026, Example 53 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 20nMAssay Description:Inhibition of Toxoplasma gondii CDPK1 assessed as ATP consumption using (Biotin-C6-PLARTLSVAGLPGKK) as substrate after 90 mins by luciferase reporter...More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2NK3GXDPubMed
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148647(CHEMBL3769570 | US9518026, Example 53 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 41nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JN4US Patent
TargetUncharacterized protein(Cryptosporidium parvum)
University of Washington Through its Center For Commercialization

US Patent
LigandPNGBDBM50148647(CHEMBL3769570 | US9518026, Example 53 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 21nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q2BV7JN4US Patent
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))TBA
LigandPNGBDBM50148647(CHEMBL3769570 | US9518026, Example 53 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RSJPubMed
TargetCalcium-dependent protein kinase 1(Cryptosporidium parvum)
Boehringer Ingelheim (Canada) Ltd.

LigandPNGBDBM50148647(CHEMBL3769570 | US9518026, Example 53 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 5nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G91US Patent
LigandPNGBDBM50148647(CHEMBL3769570 | US9518026, Example 53 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human ERG by thallium flux assayMore data for this Ligand-Target Pair
In DepthDetails Article
BindingDB Entry DOI: 10.7270/Q2GT5RSJPubMed
TargetCalmodulin-domain protein kinase 1(Toxoplasma gondii)
University of Washington

Curated by ChEMBL
LigandPNGBDBM50148647(CHEMBL3769570 | US9518026, Example 53 | US9956214,...)copy SMILEScopy InChI
Affinity DataIC50: 17nMAssay Description:Inhibition of TgCDPK1 and CpCDPK1 was determined using a luminescent kinase assay which measures ATP depletion in the presence of the Syntide 2 pepti...More data for this Ligand-Target Pair
In DepthDetails
BindingDB Entry DOI: 10.7270/Q23J3G91US Patent